@article{RN32, author = {Abitua, Philip B and Aksel, Deniz C and Schier, Alexander F}, title = {Axis formation in annual killifish: Nodal coordinates morphogenesis in absence of Huluwa prepatterning}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN42, author = {Absalon, Sabrina and Dvorin, Jeffrey D}, title = {Depletion of the mini‐chromosome maintenance complex binding protein allows the progression of cytokinesis despite abnormal karyokinesis during the asexual development of Plasmodium falciparum}, journal = {Cellular microbiology}, volume = {23}, number = {3}, pages = {e13284}, ISSN = {1462-5814}, year = {2021}, type = {Journal Article} } @article{RN75, author = {Amamoto, Ryoji and Zuccaro, Emanuela and Curry, Nathan C and Khurana, Sonia and Chen, Hsu-Hsin and Cepko, Constance L and Arlotta, Paola}, title = {FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system}, journal = {Nucleic Acids Research}, volume = {48}, number = {1}, pages = {e4-e4}, ISSN = {0305-1048}, year = {2020}, type = {Journal Article} } @article{RN49, author = {Amin, Ladan and Harris, David A}, title = {Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers}, journal = {Nature Communications}, volume = {12}, number = {1}, pages = {1-16}, ISSN = {2041-1723}, year = {2021}, type = {Journal Article} } @unpublished{RN18, author = {Anand, Giridhar M. and Megale, Heitor C. and Murphy, Sean H. and Weis, Theresa and Lin, Zuwan and He, Yichun and Wang, Xiao and Liu, Jia and Ramanathan, Sharad}, title = {Machine learning directed organoid morphogenesis uncovers an excitable system driving human axial elongation}, publisher = {Cold Spring Harbor Laboratory}, DOI = {10.1101/2022.05.10.491358}, url = {https://dx.doi.org/10.1101/2022.05.10.491358}, year = {2022}, type = {Unpublished Work} } @article{RN50, author = {Baum, Matthew L and Wilton, Daniel K and Muthukumar, Allie and Fox, Rachel G and Carey, Alanna and Crotty, William and Scott-Hewitt, Nicole and Bien, Elizabeth and Sabatini, David A and Lanser, Toby}, title = {CUB and Sushi Multiple Domains 1 (CSMD1) opposes the complement cascade in neural tissues}, journal = {bioRxiv}, year = {2020}, type = {Journal Article} } @article{RN68, author = {Bloom, Maria Lissitsyna and Johnston, Lucille B and Datta, Sandeep Robert}, title = {Renewal and differentiation of GCD necklace olfactory sensory neurons}, journal = {Chemical senses}, volume = {45}, number = {5}, pages = {333-346}, ISSN = {0379-864X}, year = {2020}, type = {Journal Article} } @article{RN47, author = {Carman, Christopher V and Nikova, Dessislava N and Sakurai, Yumiko and Shi, Jialan and Novakovic, Valerie A and Rasmussen, Jan T and Lam, Wilbur and Gilbert, Gary E}, title = {Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells}, journal = {Blood Advances}, ISSN = {2473-9529}, year = {2022}, type = {Journal Article} } @article{RN20, author = {Chun, Justin and Riella, Cristian V. and Chung, Hyunjae and Shah, Shrijal S. and Wang, Minxian and Magraner, Jose M. and Ribas, Guilherme T. and Ribas, Hennrique T. and Zhang, Jia-Yue and Alper, Seth L. and Friedman, David J. and Pollak, Martin R.}, title = {DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants}, journal = {Journal of the American Society of Nephrology}, volume = {33}, number = {5}, pages = {889-907}, ISSN = {1046-6673}, DOI = {10.1681/asn.2021050723}, url = {https://dx.doi.org/10.1681/asn.2021050723}, year = {2022}, type = {Journal Article} } @article{RN80, author = {Churgin, Matthew and Lavrentovich, Danylo and Smith, Matthew AY and Gao, Ruixuan and Boyden, Edward S and de Bivort, Benjamin L}, title = {Neural correlates of individual odor preference in Drosophila}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN95, author = {Churgin, Matthew and Lavrentovich, Danylo and Smith, Matthew AY and Gao, Ruixuan and Boyden, Edward S and de Bivort, Benjamin L}, title = {Neural correlates of individual odor preference in Drosophila}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN22, author = {Clements, Rebecca L. and Morano, Alexander A. and Navarro, Francesca M. and McGee, James P. and Du, Esrah W. and Streva, Vincent A. and Lindner, Scott E. and Dvorin, Jeffrey D.}, title = {Identification of basal complex protein that is essential for maturation of transmission-stage malaria parasites}, journal = {Proceedings of the National Academy of Sciences}, volume = {119}, number = {34}, pages = {e2204167119}, note = {doi: 10.1073/pnas.2204167119}, abstract = {Malaria remains a global driver of morbidity and mortality. To generate new antimalarials, one must elucidate the fundamental cell biology of Plasmodium falciparum, the parasite responsible for the deadliest cases of malaria. A membranous and proteinaceous scaffold called the inner membrane complex (IMC) supports the parasite during morphological changes, including segmentation of daughter cells during asexual replication and formation of transmission-stage gametocytes. The basal complex lines the edge of the IMC during segmentation and likely facilitates IMC expansion. It is unknown, however, what drives IMC expansion during gametocytogenesis. We describe the discovery of a basal complex protein, PfBLEB, which we find to be essential for gametocytogenesis. Parasites lacking PfBLEB harbor defects in IMC expansion and are unable to form mature gametocytes. This article demonstrates a role for a basal complex protein outside of asexual division, and, importantly, highlights a potential molecular target for the ablation of malaria transmission.}, DOI = {10.1073/pnas.2204167119}, url = {https://doi.org/10.1073/pnas.2204167119}, year = {2022}, type = {Journal Article} } @article{RN37, author = {Davis, Jeffrey C and Alves, Tiago C and Helman, Aharon and Chen, Jonathan C and Kenty, Jennifer H and Cardone, Rebecca L and Liu, David R and Kibbey, Richard G and Melton, Douglas A}, title = {Glucose response by stem cell-derived β cells in vitro is inhibited by a bottleneck in glycolysis}, journal = {Cell reports}, volume = {31}, number = {6}, pages = {107623}, ISSN = {2211-1247}, year = {2020}, type = {Journal Article} } @article{RN61, author = {Donoughe, Seth and Hoffmann, Jordan and Nakamura, Taro and Rycroft, Chris H and Extavour, Cassandra G}, title = {Local density determines nuclear movements during syncytial blastoderm formation in a cricket}, journal = {BioRxiv}, year = {2021}, type = {Journal Article} } @article{RN27, author = {Donoughe, Seth and Hoffmann, Jordan and Nakamura, Taro and Rycroft, Chris H and Extavour, Cassandra G}, title = {Nuclear speed and cycle length co-vary with local density during syncytial blastoderm formation in a cricket}, journal = {Nature communications}, volume = {13}, number = {1}, pages = {1-14}, ISSN = {2041-1723}, year = {2022}, type = {Journal Article} } @article{RN44, author = {Evans, Michael A and Shields IV, C Wyatt and Krishnan, Vinu and Wang, Lily Li‐Wen and Zhao, Zhongmin and Ukidve, Anvay and Lewandowski, Michael and Gao, Yongsheng and Mitragotri, Samir}, title = {Macrophage‐Mediated Delivery of Hypoxia‐Activated Prodrug Nanoparticles}, journal = {Advanced Therapeutics}, volume = {3}, number = {2}, pages = {1900162}, ISSN = {2366-3987}, year = {2020}, type = {Journal Article} } @article{RN58, author = {Freedman, Benjamin R and Kuttler, Andreas and Beckmann, Nicolau and Nam, Sungmin and Kent, Daniel and Schuleit, Michael and Ramazani, Farshad and Accart, Nathalie and Rock, Anna and Li, Jianyu}, title = {Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity}, journal = {Nature Biomedical Engineering}, pages = {1-13}, ISSN = {2157-846X}, year = {2022}, type = {Journal Article} } @article{RN43, author = {Garbern, Jessica C and Helman, Aharon and Sereda, Rebecca and Sarikhani, Mohsen and Ahmed, Aishah and Escalante, Gabriela O and Ogurlu, Roza and Kim, Sean L and Zimmerman, John F and Cho, Alexander}, title = {Inhibition of mTOR signaling enhances maturation of cardiomyocytes derived from human-induced pluripotent stem cells via p53-induced quiescence}, journal = {Circulation}, volume = {141}, number = {4}, pages = {285-300}, ISSN = {0009-7322}, year = {2020}, type = {Journal Article} } @article{RN9, author = {Giribet, Gonzalo and Baker, Caitlin M. and Brouste, Damien}, title = {Martensopsalis, a new genus of Neopilionidae from New Caledonia (Opiliones: Eupnoi)}, journal = {Zootaxa}, volume = {4984}, number = {1}, pages = {98-107}, ISSN = {1175-5334}, DOI = {10.11646/zootaxa.4984.1.9}, url = {https://dx.doi.org/10.11646/zootaxa.4984.1.9}, year = {2021}, type = {Journal Article} } @article{RN23, author = {Grolman, Joshua M and Weinand, Philipp and Mooney, David J}, title = {Extracellular matrix plasticity as a driver of cell spreading}, journal = {Proceedings of the National Academy of Sciences}, volume = {117}, number = {42}, pages = {25999-26007}, ISSN = {0027-8424}, year = {2020}, type = {Journal Article} } @article{RN56, author = {Guitchounts, Grigori and Masis, Javier and Wolff, Steffen BE and Cox, David}, title = {Encoding of 3D head orienting movements in the primary visual cortex}, journal = {Neuron}, volume = {108}, number = {3}, pages = {512-525. e4}, ISSN = {0896-6273}, year = {2020}, type = {Journal Article} } @article{RN82, author = {Hao, Jin and Wells, Michael F and Niu, Gengle and San Juan, Irune Guerra and Limone, Francesco and Fukuda, Atsushi and Leyton-Jaimes, Marcel F and Joseph, Brian and Qian, Menglu and Mordes, Daniel A}, title = {Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN93, author = {Hao, Jin and Wells, Michael F and Niu, Gengle and San Juan, Irune Guerra and Limone, Francesco and Fukuda, Atsushi and Leyton-Jaimes, Marcel F and Joseph, Brian and Qian, Menglu and Mordes, Daniel A}, title = {Loss of TBK1 activity leads to TDP-43 proteinopathy through lysosomal dysfunction in human motor neurons}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN86, author = {Harada, Taku and Heshmati, Yaser and Kalfon, Jérémie and Perez, Monika W and Ferrucio, Juliana Xavier and Ewers, Jazmin and Engler, Benjamin Hubbell and Kossenkov, Andrew and Ellegast, Jana M and Joanna, S Yi}, title = {A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia}, journal = {Genes & development}, volume = {36}, number = {5-6}, pages = {368-389}, ISSN = {0890-9369}, year = {2022}, type = {Journal Article} } @article{RN89, author = {Harada, Taku and Heshmati, Yaser and Kalfon, Jérémie and Perez, Monika W and Ferrucio, Juliana Xavier and Ewers, Jazmin and Engler, Benjamin Hubbell and Kossenkov, Andrew and Ellegast, Jana M and Joanna, S Yi}, title = {A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia}, journal = {Genes & development}, volume = {36}, number = {5-6}, pages = {368-389}, ISSN = {0890-9369}, year = {2022}, type = {Journal Article} } @article{RN16, author = {Harris, James M. and Yu-Der Wang, Andy and Arlotta, Paola}, title = {Optogenetic axon guidance in embryonic zebrafish}, journal = {STAR Protocols}, volume = {2}, number = {4}, pages = {100947}, abstract = {Summary Axons form the long-range connections of biological neuronal networks, which are built through the developmental process of axon guidance. Here, we describe a protocol to precisely and non-invasively control axonal growth trajectories in live zebrafish embryos using focal light activation of a photoactivatable Rac1. We outline techniques for photostimulation, time-lapse imaging, and immunohistochemistry. These approaches enable engineering of long-range axonal circuitry or repair of defective circuits in living zebrafish, despite a milieu of competing endogenous signals and repulsive barriers. For complete details on the use and execution of this protocol, please refer to Harris et al. (2020).}, keywords = {Developmental biology Microscopy Model Organisms Molecular Biology Neuroscience}, ISSN = {2666-1667}, DOI = {https://doi.org/10.1016/j.xpro.2021.100947}, url = {https://www.sciencedirect.com/science/article/pii/S2666166721006535}, year = {2021}, type = {Journal Article} } @article{RN79, author = {Hui, Jie and Dong, Pu‐Ting and Liang, Lijia and Mandal, Taraknath and Li, Junjie and Ulloa, Erlinda R and Zhan, Yuewei and Jusuf, Sebastian and Zong, Cheng and Seleem, Mohamed N}, title = {Photo‐disassembly of membrane microdomains revives conventional antibiotics against MRSA}, journal = {Advanced Science}, volume = {7}, number = {6}, pages = {1903117}, ISSN = {2198-3844}, year = {2020}, type = {Journal Article} } @article{RN33, author = {Hutcheson, Joshua D and Schlotter, Florian and Creager, Michael D and Li, Xiaoshuang and Pham, Tan and Vyas, Payal and Higashi, Hideyuki and Body, Simon C and Aikawa, Masanori and Singh, Sasha A}, title = {Elastogenesis correlates with pigment production in murine aortic valve leaflets}, journal = {Frontiers in Cardiovascular Medicine}, volume = {8}, pages = {533}, ISSN = {2297-055X}, year = {2021}, type = {Journal Article} } @article{RN85, author = {Itoh, Yasuhiro and Sahni, Vibhu and Shnider, Sara J and Macklis, Jeffrey D}, title = {Lumican regulates cervical corticospinal axon collateralization via non-autonomous crosstalk between distinct corticospinal neuron subpopulations}, journal = {BioRxiv}, year = {2021}, type = {Journal Article} } @article{RN90, author = {Itoh, Yasuhiro and Sahni, Vibhu and Shnider, Sara J and Macklis, Jeffrey D}, title = {Lumican regulates cervical corticospinal axon collateralization via non-autonomous crosstalk between distinct corticospinal neuron subpopulations}, journal = {BioRxiv}, year = {2021}, type = {Journal Article} } @article{RN62, author = {Johnson, Milo S and Gopalakrishnan, Shreyas and Goyal, Juhee and Dillingham, Megan E and Bakerlee, Christopher W and Humphrey, Parris T and Jagdish, Tanush and Jerison, Elizabeth R and Kosheleva, Katya and Lawrence, Katherine R}, title = {Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations}, journal = {Elife}, volume = {10}, pages = {e63910}, ISSN = {2050-084X}, year = {2021}, type = {Journal Article} } @article{RN31, author = {Kim, Jayoung and Gao, Yongsheng and Zhao, Zongmin and Rodrigues, Danika and Tanner, Eden EL and Ibsen, Kelly and Sasmal, Pradip K and Jaladi, Rajasekhar and Alikunju, Shanavas and Mitragotri, Samir}, title = {A deep eutectic-based, self-emulsifying subcutaneous depot system for apomorphine therapy in Parkinson’s disease}, journal = {Proceedings of the National Academy of Sciences}, volume = {119}, number = {9}, pages = {e2110450119}, ISSN = {0027-8424}, year = {2022}, type = {Journal Article} } @article{RN87, author = {Kingsley, Evan P and Hager, Emily R and Lassance, Jean Marc and Turner, Kyle M and Harringmeyer, Olivia S and Kirby, Christopher and Neugeboren, Beverly I and Hoekstra, Hopi E}, title = {Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN88, author = {Kingsley, Evan P and Hager, Emily R and Lassance, Jean Marc and Turner, Kyle M and Harringmeyer, Olivia S and Kirby, Christopher and Neugeboren, Beverly I and Hoekstra, Hopi E}, title = {Adaptive tail-length evolution in deer mice is associated with differential Hoxd13 expression in early development}, journal = {bioRxiv}, year = {2021}, type = {Journal Article} } @article{RN29, author = {Lau, Chunyue Geoffrey and Zhang, Huiqi and Murthy, Venkatesh N}, title = {Deletion of TrkB in parvalbumin interneurons alters cortical neural dynamics}, journal = {Journal of Cellular Physiology}, volume = {237}, number = {1}, pages = {949-964}, ISSN = {0021-9541}, year = {2022}, type = {Journal Article} } @article{RN30, author = {Lau, Chunyue Geoffrey and Zhang, Huiqi and Murthy, Venkatesh N}, title = {Deletion of TrkB in parvalbumin interneurons alters cortical neural dynamics}, journal = {Journal of Cellular Physiology}, volume = {237}, number = {1}, pages = {949-964}, ISSN = {0021-9541}, year = {2022}, type = {Journal Article} } @article{RN65, author = {Levy, Jonathan M and Yeh, Wei-Hsi and Pendse, Nachiket and Davis, Jessie R and Hennessey, Erin and Butcher, Rossano and Koblan, Luke W and Comander, Jason and Liu, Qin and Liu, David R}, title = {Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses}, journal = {Nature biomedical engineering}, volume = {4}, number = {1}, pages = {97-110}, ISSN = {2157-846X}, year = {2020}, type = {Journal Article} } @article{RN10, author = {Li, Tao and Chiou, Brian and Gilman, Casey K. and Luo, Rong and Koshi, Tatsuhiro and Yu, Diankun and Oak, Hayeon C. and Giera, Stefanie and Johnson‐Venkatesh, Erin and Muthukumar, Allie K. and Stevens, Beth and Umemori, Hisashi and Piao, Xianhua}, title = {A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding}, journal = {The EMBO Journal}, volume = {39}, number = {16}, ISSN = {0261-4189}, DOI = {10.15252/embj.2019104136}, url = {https://dx.doi.org/10.15252/embj.2019104136}, year = {2020}, type = {Journal Article} } @article{RN14, author = {Lord, Nathan D. and Carte, Adam N. and Abitua, Philip B. and Schier, Alexander F.}, title = {The pattern of nodal morphogen signaling is shaped by co-receptor expression}, journal = {eLife}, volume = {10}, ISSN = {2050-084X}, DOI = {10.7554/elife.54894}, url = {https://dx.doi.org/10.7554/elife.54894}, year = {2021}, type = {Journal Article} } @article{RN78, author = {MacMullin, Paul and Hodgson, Nathaniel and Damar, Ugur and Lee, Henry Hing Cheong and Hameed, Mustafa Q and Dhamne, Sameer C and Hyde, Damon and Conley, Grace M and Morriss, Nicholas and Qiu, Jianhua}, title = {Increase in seizure susceptibility after repetitive concussion results from oxidative stress, parvalbumin-positive interneuron dysfunction and biphasic increases in glutamate/GABA ratio}, journal = {Cerebral Cortex}, volume = {30}, number = {12}, pages = {6108-6120}, ISSN = {1047-3211}, year = {2020}, type = {Journal Article} } @article{RN96, author = {MacMullin, Paul and Hodgson, Nathaniel and Damar, Ugur and Lee, Henry Hing Cheong and Hameed, Mustafa Q and Dhamne, Sameer C and Hyde, Damon and Conley, Grace M and Morriss, Nicholas and Qiu, Jianhua}, title = {Increase in seizure susceptibility after repetitive concussion results from oxidative stress, parvalbumin-positive interneuron dysfunction and biphasic increases in glutamate/GABA ratio}, journal = {Cerebral Cortex}, volume = {30}, number = {12}, pages = {6108-6120}, ISSN = {1047-3211}, year = {2020}, type = {Journal Article} } @article{RN71, author = {Mannix, Rebekah and Morriss, Nicholas J and Conley, Grace M and Meehan III, William P and Nedder, Arthur and Qiu, Jianhua and Float, Jamison and DiCesare, Christopher A and Myer, Gregory D}, title = {Internal jugular vein compression collar mitigates histopathological alterations after closed head rotational head impact in swine: A pilot study}, journal = {Neuroscience}, volume = {437}, pages = {132-144}, ISSN = {0306-4522}, year = {2020}, type = {Journal Article} } @article{RN45, author = {Marlow, Jeffrey and Spietz, Rachel and Kim, Keun‐Young and Ellisman, Mark and Girguis, Peter and Hatzenpichler, Roland}, title = {Spatially resolved correlative microscopy and microbial identification reveal dynamic depth‐and mineral‐dependent anabolic activity in salt marsh sediment}, journal = {Environmental microbiology}, volume = {23}, number = {8}, pages = {4756-4777}, ISSN = {1462-2912}, year = {2021}, type = {Journal Article} } @article{RN69, author = {Marlow, Jeffrey J and Colocci, Isabella and Jungbluth, Sean P and Weber, Nils Moritz and Gartman, Amy and Kallmeyer, Jens}, title = {Mapping metabolic activity at single cell resolution in intact volcanic fumarole sediment}, journal = {FEMS Microbiology Letters}, volume = {367}, number = {1}, pages = {fnaa031}, ISSN = {1574-6968}, year = {2020}, type = {Journal Article} } @article{RN13, author = {Marlow, Jeffrey J. and Hoer, Daniel and Jungbluth, Sean P. and Reynard, Linda M. and Gartman, Amy and Chavez, Marko S. and El-Naggar, Mohamed Y. and Tuross, Noreen and Orphan, Victoria J. and Girguis, Peter R.}, title = {Carbonate-hosted microbial communities are prolific and pervasive methane oxidizers at geologically diverse marine methane seep sites}, journal = {Proceedings of the National Academy of Sciences}, volume = {118}, number = {25}, pages = {e2006857118}, ISSN = {0027-8424}, DOI = {10.1073/pnas.2006857118}, url = {https://dx.doi.org/10.1073/pnas.2006857118}, year = {2021}, type = {Journal Article} } @article{RN60, author = {Martenson, James S and Tam, Hanson and McQuown, Alexander J and Reif, Dvir and Zhou, Jing and Denic, Vladimir}, title = {The importomer is a peroxisomal membrane protein translocase}, journal = {bioRxiv}, year = {2020}, type = {Journal Article} } @article{RN53, author = {Martiros, Nuné and Kapoor, Vikrant and Kim, Spencer E and Murthy, Venkatesh N}, title = {Distinct representation of cue-outcome association by D1 and D2 neurons in the ventral striatum’s olfactory tubercle}, journal = {Elife}, volume = {11}, pages = {e75463}, ISSN = {2050-084X}, year = {2022}, type = {Journal Article} } @article{RN59, author = {Mayweather, Brittany A and Buchanan, Sean M and Rubin, Lee L}, title = {GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis}, journal = {Molecular brain}, volume = {14}, number = {1}, pages = {1-13}, ISSN = {1756-6606}, year = {2021}, type = {Journal Article} } @article{RN74, author = {McCarthy, Gizelle M and Blasio, Angelo and Donovan, Olivia G and Schaller, Lena B and Bock-Hughes, Althea and Magraner, Jose M and Suh, Jung Hee and Tattersfield, Calum F and Stillman, Isaac E and Shah, Shrijal S}, title = {Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease}, journal = {Disease Models & Mechanisms}, volume = {14}, number = {8}, pages = {dmm048952}, ISSN = {1754-8403}, year = {2021}, type = {Journal Article} } @article{RN55, author = {Mills, Evanna L and Harmon, Cathal and Jedrychowski, Mark P and Xiao, Haopeng and Garrity, Ryan and Tran, Nhien V and Bradshaw, Gary A and Fu, Accalia and Szpyt, John and Reddy, Anita}, title = {UCP1 governs liver extracellular succinate and inflammatory pathogenesis}, journal = {Nature metabolism}, volume = {3}, number = {5}, pages = {604-617}, ISSN = {2522-5812}, year = {2021}, type = {Journal Article} } @article{RN39, author = {Min, Ya and Ballerini, Evangeline S and Edwards, Molly B and Hodges, Scott A and Kramer, Elena M}, title = {Genetic architecture underlying variation in floral meristem termination in Aquilegia}, journal = {Journal of Experimental Botany}, abstract = {Floral organs are produced by floral meristems (FMs), which harbor stem cells in their centers. Since each flower only has a finite number of organs, the stem cell activity of an FM will always terminate at a specific time point, a process termed floral meristem termination (FMT). Variation in the timing of FMT can give rise to floral morphological diversity, but how this process is fine-tuned at a developmental and evolutionary level is poorly understood. Flowers from the genus Aquilegia share identical floral organ arrangement except for stamen whorl number (SWN), making Aquilegia a well-suited system for investigation of this process: differences in SWN between species represent differences in the timing of FMT. By crossing A. canadensis and A. brevistyla, quantitative trait locus (QTL) mapping has revealed a complex genetic architecture with seven QTL. We explored potential candidate genes under each QTL and characterized novel expression patterns of select loci of interest using in situ hybridization. To our knowledge, this is the first attempt to dissect the genetic basis of how natural variation in the timing of FMT is regulated, and our results provide insight into how floral morphological diversity can be generated at the meristematic level.}, ISSN = {0022-0957}, DOI = {10.1093/jxb/erac277}, url = {https://doi.org/10.1093/jxb/erac277}, year = {2022}, type = {Journal Article} } @article{RN38, author = {Mordes, Daniel A and Morrison, Brett M and Ament, Xanthe H and Cantrell, Christopher and Mok, Joanie and Eggan, Pierce and Xue, Carolyn and Wang, Jin-Yuan and Eggan, Kevin and Rothstein, Jeffrey D}, title = {Absence of survival and motor deficits in 500 repeat C9ORF72 BAC mice}, journal = {Neuron}, volume = {108}, number = {4}, pages = {775-783. e4}, ISSN = {0896-6273}, year = {2020}, type = {Journal Article} } @article{RN70, author = {Morriss, Nicholas J and Conley, Grace M and Ospina, Sara M and Meehan III, William P and Qiu, Jianhua and Mannix, Rebekah}, title = {Automated quantification of immunohistochemical staining of large animal brain tissue using QuPath software}, journal = {Neuroscience}, volume = {429}, pages = {235-244}, ISSN = {0306-4522}, year = {2020}, type = {Journal Article} } @article{RN3, author = {Nagarkar, A. A. and Root, S. E. and Fink, M. J. and Ten, A. S. and Cafferty, B. J. and Richardson, D. S. and Mrksich, M. and Whitesides, G. M.}, title = {Storing and Reading Information in Mixtures of Fluorescent Molecules}, journal = {ACS Cent Sci}, volume = {7}, number = {10}, pages = {1728-1735}, note = {Nagarkar, Amit A Root, Samuel E Fink, Michael J Ten, Alexei S Cafferty, Brian J Richardson, Douglas S Mrksich, Milan Whitesides, George M eng 2021/11/04 ACS Cent Sci. 2021 Oct 27;7(10):1728-1735. doi: 10.1021/acscentsci.1c00728. Epub 2021 Oct 13.}, abstract = {The rapidly increasing use of digital technologies requires the rethinking of methods to store data. This work shows that digital data can be stored in mixtures of fluorescent dye molecules, which are deposited on a surface by inkjet printing, where an amide bond tethers the dye molecules to the surface. A microscope equipped with a multichannel fluorescence detector distinguishes individual dyes in the mixture. The presence or absence of these molecules in the mixture encodes binary information (i.e., "0" or "1"). The use of mixtures of molecules, instead of sequence-defined macromolecules, minimizes the time and difficulty of synthesis and eliminates the requirement of sequencing. We have written, stored, and read a total of approximately 400 kilobits (both text and images) with greater than 99% recovery of information, written at an average rate of 128 bits/s (16 bytes/s) and read at a rate of 469 bits/s (58.6 bytes/s).}, ISSN = {2374-7943 (Print) 2374-7943 (Linking)}, DOI = {10.1021/acscentsci.1c00728}, url = {https://www.ncbi.nlm.nih.gov/pubmed/34729416}, year = {2021}, type = {Journal Article} } @article{RN15, author = {Odstrcil, Iris and Petkova, Mariela D. and Haesemeyer, Martin and Boulanger-Weill, Jonathan and Nikitchenko, Maxim and Gagnon, James A. and Oteiza, Pablo and Schalek, Richard and Peleg, Adi and Portugues, Ruben and Lichtman, Jeff W. and Engert, Florian}, title = {Functional and ultrastructural analysis of reafferent mechanosensation in larval zebrafish}, journal = {Current Biology}, volume = {32}, number = {1}, pages = {176-189.e5}, ISSN = {0960-9822}, DOI = {10.1016/j.cub.2021.11.007}, url = {https://dx.doi.org/10.1016/j.cub.2021.11.007}, year = {2022}, type = {Journal Article} } @article{RN8, author = {Prahst, Claudia and Ashrafzadeh, Parham and Mead, Thomas and Figueiredo, Ana and Chang, Karen and Richardson, Douglas and Venkaraman, Lakshmi and Richards, Mark and Russo, Ana Martins and Harrington, Kyle and Ouarné, Marie and Pena, Andreia and Chen, Dong Feng and Claesson-Welsh, Lena and Cho, Kin-Sang and Franco, Claudio A. and Bentley, Katie}, title = {Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy}, journal = {eLife}, volume = {9}, ISSN = {2050-084X}, DOI = {10.7554/elife.49779}, url = {https://dx.doi.org/10.7554/elife.49779}, year = {2020}, type = {Journal Article} } @article{RN48, author = {Rapoport, Leonid and Emmerich, Theo and Varanasi, Kripa K}, title = {Capturing bubbles and preventing foam using aerophilic surfaces}, journal = {Advanced Materials Interfaces}, volume = {7}, number = {6}, pages = {1901599}, ISSN = {2196-7350}, year = {2020}, type = {Journal Article} } @article{RN76, author = {Reddy, Anita and Bozi, Luiz HM and Yaghi, Omar K and Mills, Evanna L and Xiao, Haopeng and Nicholson, Hilary E and Paschini, Margherita and Paulo, Joao A and Garrity, Ryan and Laznik-Bogoslavski, Dina}, title = {pH-gated succinate secretion regulates muscle remodeling in response to exercise}, journal = {Cell}, volume = {183}, number = {1}, pages = {62-75. e17}, ISSN = {0092-8674}, year = {2020}, type = {Journal Article} } @article{RN1, author = {Richardson, D. S. and Guan, W. and Matsumoto, K. and Pan, C. and Chung, K. and Erturk, A. and Ueda, H. R. and Lichtman, J. W.}, title = {Tissue Clearing}, journal = {Nat Rev Methods Primers}, volume = {1}, number = {1}, note = {Richardson, Douglas S Guan, Webster Matsumoto, Katsuhiko Pan, Chenchen Chung, Kwanghun Erturk, Ali Ueda, Hiroki R Lichtman, Jeff W eng DP2 ES027992/ES/NIEHS NIH HHS/ P50 MH094271/MH/NIMH NIH HHS/ U01 MH117072/MH/NIMH NIH HHS/ U19 NS104653/NS/NINDS NIH HHS/ England 2022/02/08 Nat Rev Methods Primers. 2021;1(1). doi: 10.1038/s43586-021-00080-9. Epub 2021 Dec 16.}, abstract = {Tissue clearing of gross anatomical samples was first described over a century ago and has only recently found widespread use in the field of microscopy. This renaissance has been driven by the application of modern knowledge of optical physics and chemical engineering to the development of robust and reproducible clearing techniques, the arrival of new microscopes that can image large samples at cellular resolution and computing infrastructure able to store and analyze large data volumes. Many biological relationships between structure and function require investigation in three dimensions and tissue clearing therefore has the potential to enable broad discoveries in the biological sciences. Unfortunately, the current literature is complex and could confuse researchers looking to begin a clearing project. The goal of this Primer is to outline a modular approach to tissue clearing that allows a novice researcher to develop a customized clearing pipeline tailored to their tissue of interest. Further, the Primer outlines the required imaging and computational infrastructure needed to perform tissue clearing at scale, gives an overview of current applications, discusses limitations and provides an outlook on future advances in the field.}, ISSN = {2662-8449 (Electronic) 2662-8449 (Linking)}, DOI = {10.1038/s43586-021-00080-9}, url = {https://www.ncbi.nlm.nih.gov/pubmed/35128463}, year = {2021}, type = {Journal Article} } @article{RN21, author = {Rogers, Maximillian A. and Buffolo, Fabrizio and Schlotter, Florian and Atkins, Samantha K. and Lee, Lang H. and Halu, Arda and Blaser, Mark C. and Tsolaki, Elena and Higashi, Hideyuki and Luther, Kristin and Daaboul, George and Bouten, Carlijn V.C. and Body, Simon C. and Singh, Sasha A. and Bertazzo, Sergio and Libby, Peter and Aikawa, Masanori and Aikawa, Elena}, title = {Annexin A1–dependent tethering promotes extracellular vesicle aggregation revealed with single–extracellular vesicle analysis}, journal = {Science Advances}, volume = {6}, number = {38}, pages = {eabb1244}, abstract = {Protein-mediated tethering of vesicles in the extracellular matrix contributes to microcalcification formation. Extracellular vesicles (EVs) including plasma membrane–derived microvesicles and endosomal-derived exosomes aggregate by unknown mechanisms, forming microcalcifications that promote cardiovascular disease, the leading cause of death worldwide. Here, we show a framework for assessing cell-independent EV mechanisms in disease by suggesting that annexin A1 (ANXA1)–dependent tethering induces EV aggregation and microcalcification. We present single-EV microarray, a method to distinguish microvesicles from exosomes and assess heterogeneity at a single-EV level. Single-EV microarray and proteomics revealed increased ANXA1 primarily on aggregating and calcifying microvesicles. ANXA1 vesicle aggregation was suppressed by calcium chelation, altering pH, or ANXA1 neutralizing antibody. ANXA1 knockdown attenuated EV aggregation and microcalcification formation in human cardiovascular cells and acellular three-dimensional collagen hydrogels. Our findings explain why microcalcifications are more prone to form in vulnerable regions of plaque, regulating critical cardiovascular pathology, and likely extend to other EV-associated diseases, including autoimmune and neurodegenerative diseases and cancer.}, DOI = {doi:10.1126/sciadv.abb1244}, url = {https://www.science.org/doi/abs/10.1126/sciadv.abb1244}, year = {2020}, type = {Journal Article} } @article{RN11, author = {Russo, Brian C. and Duncan-Lowey, Jeffrey K. and Chen, Poyin and Goldberg, Marcia B.}, title = {The type 3 secretion system requires actin polymerization to open translocon pores}, journal = {PLOS Pathogens}, volume = {17}, number = {9}, pages = {e1009932}, ISSN = {1553-7374}, DOI = {10.1371/journal.ppat.1009932}, url = {https://dx.doi.org/10.1371/journal.ppat.1009932}, year = {2021}, type = {Journal Article} } @article{RN81, author = {Sahni, Vibhu and Itoh, Yasuhiro and Shnider, Sara J and Macklis, Jeffrey D}, title = {Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting}, journal = {Cell reports}, volume = {37}, number = {3}, pages = {109842}, ISSN = {2211-1247}, year = {2021}, type = {Journal Article} } @article{RN94, author = {Sahni, Vibhu and Itoh, Yasuhiro and Shnider, Sara J and Macklis, Jeffrey D}, title = {Crim1 and Kelch-like 14 exert complementary dual-directional developmental control over segmentally specific corticospinal axon projection targeting}, journal = {Cell reports}, volume = {37}, number = {3}, pages = {109842}, ISSN = {2211-1247}, year = {2021}, type = {Journal Article} } @article{RN73, author = {Sahni, Vibhu and Shnider, Sara J and Jabaudon, Denis and Song, Janet HT and Itoh, Yasuhiro and Greig, Luciano C and Macklis, Jeffrey D}, title = {Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting}, journal = {Cell reports}, volume = {37}, number = {3}, pages = {109843}, ISSN = {2211-1247}, year = {2021}, type = {Journal Article} } @unpublished{RN19, author = {Salcedo, Mary K. and Jun, Brian and Vlachos, Pavlos and Mahadevan, Lakshminarayanan and Combes, Stacey A.}, title = {Viscous effects and complex local flow behaviors dominate hemolymph circulation in the living wings of locusts}, publisher = {Cold Spring Harbor Laboratory}, DOI = {10.1101/2021.09.15.460448}, url = {https://dx.doi.org/10.1101/2021.09.15.460448}, year = {2021}, type = {Unpublished Work} } @article{RN25, author = {San Juan, Irune Guerra and Nash, Leslie A and Smith, Kevin S and Leyton-Jaimes, Marcel F and Qian, Menglu and Klim, Joseph R and Limone, Francesco and Dorr, Alexander B and Couto, Alexander and Pintacuda, Greta}, title = {Loss of mouse Stmn2 function causes motor neuropathy}, journal = {Neuron}, volume = {110}, number = {10}, pages = {1671-1688. e6}, ISSN = {0896-6273}, year = {2022}, type = {Journal Article} } @article{RN51, author = {Sarikhani, Mohsen and Garbern, Jessica C and Ma, Sai and Sereda, Rebecca and Conde, Jeffrey and Krähenbühl, Guido and Escalante, Gabriela O and Ahmed, Aishah and Buenrostro, Jason D and Lee, Richard T}, title = {Sustained activation of AMPK enhances differentiation of human iPSC-derived cardiomyocytes via sirtuin activation}, journal = {Stem cell reports}, volume = {15}, number = {2}, pages = {498-514}, ISSN = {2213-6711}, year = {2020}, type = {Journal Article} } @article{RN72, author = {Schmieder, Stefanie S and Tatituri, Raju and Anderson, Michael and Kelly, Kate and Lencer, Wayne I}, title = {Structural basis for acyl chain control over glycosphingolipid sorting and vesicular trafficking}, journal = {Cell reports}, volume = {40}, number = {2}, pages = {111063}, ISSN = {2211-1247}, year = {2022}, type = {Journal Article} } @article{RN66, author = {Sekar, Praveen K and Liang, Xin M and Kahng, Seong-Joong and Shu, Zhiquan and Dichiara, Anthony B and Chung, Jae-Hyun and Wu, Yanyun and Gao, Dayong}, title = {Simultaneous multiparameter whole blood hemostasis assessment using a carbon nanotube-paper composite capacitance sensor}, journal = {Biosensors and Bioelectronics}, volume = {197}, pages = {113786}, ISSN = {0956-5663}, year = {2022}, type = {Journal Article} } @article{RN40, author = {Seo, Bo Ri and Payne, Christopher J and McNamara, Stephanie L and Freedman, Benjamin R and Kwee, Brian J and Nam, Sungmin and de Lázaro, Irene and Darnell, Max and Alvarez, Jonathan T and Dellacherie, Maxence O}, title = {Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils}, journal = {Science translational medicine}, volume = {13}, number = {614}, pages = {eabe8868}, ISSN = {1946-6242}, year = {2021}, type = {Journal Article} } @article{RN63, author = {Shah, Anu and Dagdeviren, Sezin and Lewandowski, Jordan P and Schmider, Angela B and Ricci-Blair, Elisabeth M and Natarajan, Niranjana and Hundal, Henna and Noh, Hye Lim and Friedline, Randall H and Vidoudez, Charles}, title = {Thioredoxin interacting protein is required for a chronic energy-rich diet to promote intestinal fructose absorption}, journal = {IScience}, volume = {23}, number = {9}, pages = {101521}, ISSN = {2589-0042}, year = {2020}, type = {Journal Article} } @article{RN57, author = {Skylar-Scott, Mark A and Huang, Jeremy Y and Lu, Aric and Ng, Alex HM and Duenki, Tomoya and Liu, Songlei and Nam, Lucy L and Damaraju, Sarita and Church, George M and Lewis, Jennifer A}, title = {Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues}, journal = {Nature Biomedical Engineering}, volume = {6}, number = {4}, pages = {449-462}, ISSN = {2157-846X}, year = {2022}, type = {Journal Article} } @article{RN83, author = {Subramanian, Balajikarthick and Chun, Justin and Perez-Gill, Chandra and Yan, Paul and Stillman, Isaac E and Higgs, Henry N and Alper, Seth L and Schlöndorff, Johannes S and Pollak, Martin R}, title = {FSGS-causing INF2 mutation impairs cleaved INF2 N-fragment functions in podocytes}, journal = {Journal of the American Society of Nephrology}, volume = {31}, number = {2}, pages = {374-391}, ISSN = {1046-6673}, year = {2020}, type = {Journal Article} } @article{RN92, author = {Subramanian, Balajikarthick and Chun, Justin and Perez-Gill, Chandra and Yan, Paul and Stillman, Isaac E and Higgs, Henry N and Alper, Seth L and Schlöndorff, Johannes S and Pollak, Martin R}, title = {FSGS-causing INF2 mutation impairs cleaved INF2 N-fragment functions in podocytes}, journal = {Journal of the American Society of Nephrology}, volume = {31}, number = {2}, pages = {374-391}, ISSN = {1046-6673}, year = {2020}, type = {Journal Article} } @article{RN7, author = {Tosic, I. and Heppler, L. N. and Egusquiaguirre, S. P. and Boehnke, N. and Correa, S. and Costa, D. F. and Moore, E. A. G. and Pal, S. and Richardson, D. S. and Ivanov, A. R. and Haas-Kogan, D. A. and Nomura, D. K. and Hammond, P. T. and Frank, D. A.}, title = {Lipidome-based Targeting of STAT3-driven Breast Cancer Cells Using Poly-l-glutamic Acid-coated Layer-by-Layer Nanoparticles}, journal = {Mol Cancer Ther}, volume = {20}, number = {4}, pages = {726-738}, note = {Tosic, Isidora Heppler, Lisa N Egusquiaguirre, Susana P Boehnke, Natalie Correa, Santiago Costa, Daniel F Moore, Elizabeth A Grossman Pal, Sharmistha Richardson, Douglas S Ivanov, Alexander R Haas-Kogan, Daphne A Nomura, Daniel K Hammond, Paula T Frank, David A eng R01 CA160979/CA/NCI NIH HHS/ R01 CA218500/CA/NCI NIH HHS/ R01 GM120272/GM/NIGMS NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't 2021/02/05 Mol Cancer Ther. 2021 Apr;20(4):726-738. doi: 10.1158/1535-7163.MCT-20-0505. Epub 2021 Feb 3.}, abstract = {The oncogenic transcription factor STAT3 is aberrantly activated in 70% of breast cancers, including nearly all triple-negative breast cancers (TNBCs). Because STAT3 is difficult to target directly, we considered whether metabolic changes driven by activated STAT3 could provide a therapeutic opportunity. We found that STAT3 prominently modulated several lipid classes, with most profound effects on N-acyl taurine and arachidonic acid, both of which are involved in plasma membrane remodeling. To exploit these metabolic changes therapeutically, we screened a library of layer-by-layer (LbL) nanoparticles (NPs) differing in the surface layer that modulates interactivity with the cell membrane. We found that poly-l-glutamic acid (PLE)-coated NPs bind to STAT3-transformed breast cancer cells with 50% greater efficiency than to nontransformed cells, and the heightened PLE-NP binding to TNBC cells was attenuated by STAT3 inhibition. This effect was also observed in densely packed three-dimensional breast cancer organoids. As STAT3-transformed cells show greater resistance to cytotoxic agents, we evaluated whether enhanced targeted delivery via PLE-NPs would provide a therapeutic advantage. We found that cisplatin-loaded PLE-NPs induced apoptosis of STAT3-driven cells at lower doses compared with both unencapsulated cisplatin and cisplatin-loaded nontargeted NPs. In addition, because radiation is commonly used in breast cancer treatment, and may alter cellular lipid distribution, we analyzed its effect on PLE-NP-cell binding. Irradiation of cells enhanced the STAT3-targeting properties of PLE-NPs in a dose-dependent manner, suggesting potential synergies between these therapeutic modalities. These findings suggest that cellular lipid changes driven by activated STAT3 may be exploited therapeutically using unique LbL NPs.}, keywords = {Drug Delivery Systems/*methods Glutamic Acid/pharmacology/*therapeutic use Humans Lipidomics/*methods Nanoparticles/*metabolism STAT3 Transcription Factor/*metabolism Triple Negative Breast Neoplasms/*genetics/pathology}, ISSN = {1538-8514 (Electronic) 1535-7163 (Linking)}, DOI = {10.1158/1535-7163.MCT-20-0505}, url = {https://www.ncbi.nlm.nih.gov/pubmed/33536189}, year = {2021}, type = {Journal Article} } @article{RN34, author = {Touloumes, George J and Ardoña, Herdeline Ann M and Casalino, Evan K and Zimmerman, John F and Chantre, Christophe O and Bitounis, Dimitrios and Demokritou, Philip and Parker, Kevin Kit}, title = {Mapping 2D-and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues}, journal = {NanoImpact}, volume = {17}, pages = {100208}, ISSN = {2452-0748}, year = {2020}, type = {Journal Article} } @article{RN77, author = {Valcourt, James R and Huang, Roya and Kundu, Sharmistha and Venkatasubramanian, Divya and Kingston, Robert E and Ramanathan, Sharad}, title = {Changing the Waddington landscape to control mesendoderm competence}, journal = {bioRxiv}, pages = {867010}, year = {2020}, type = {Journal Article} } @article{RN52, author = {Valcourt, James R and Huang, Roya E and Kundu, Sharmistha and Venkatasubramanian, Divya and Kingston, Robert E and Ramanathan, Sharad}, title = {Modulating mesendoderm competence during human germ layer differentiation}, journal = {Cell reports}, volume = {37}, number = {6}, pages = {109990}, ISSN = {2211-1247}, year = {2021}, type = {Journal Article} } @article{RN26, author = {Van der Ven, Casper FT and Tibbitt, Mark W and Conde, João and Van Mil, Alain and Hjortnaes, Jesper and Doevendans, Pieter A and Sluijter, Joost PG and Aikawa, Elena and Langer, Robert S}, title = {Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel}, journal = {Nanoscale}, volume = {13}, number = {48}, pages = {20451-20461}, year = {2021}, type = {Journal Article} } @article{RN41, author = {Van Gastel, Nick and Spinelli, Jessica B and Sharda, Azeem and Schajnovitz, Amir and Baryawno, Ninib and Rhee, Catherine and Oki, Toshihiko and Grace, Eliane and Soled, Heather J and Milosevic, Jelena}, title = {Induction of a timed metabolic collapse to overcome cancer chemoresistance}, journal = {Cell metabolism}, volume = {32}, number = {3}, pages = {391-403. e6}, ISSN = {1550-4131}, year = {2020}, type = {Journal Article} } @article{RN67, author = {Van Gastel, Nick and Stegen, Steve and Eelen, Guy and Schoors, Sandra and Carlier, Aurélie and Daniëls, Veerle W and Baryawno, Ninib and Przybylski, Dariusz and Depypere, Maarten and Stiers, Pieter-Jan}, title = {Lipid availability determines fate of skeletal progenitor cells via SOX9}, journal = {Nature}, volume = {579}, number = {7797}, pages = {111-117}, ISSN = {1476-4687}, year = {2020}, type = {Journal Article} } @article{RN64, author = {Wee, Caroline L and Song, Erin and Nikitchenko, Maxim and Herrera, Kristian J and Wong, Sandy and Engert, Florian and Kunes, Sam}, title = {Social isolation modulates appetite and defensive behavior via a common oxytocinergic circuit in larval zebrafish}, journal = {bioRxiv}, pages = {2020.02. 19.956854}, year = {2021}, type = {Journal Article} } @article{RN54, author = {Wee, Caroline L and Song, Erin and Nikitchenko, Maxim and Herrera, Kristian J and Wong, Sandy and Engert, Florian and Kunes, Samuel}, title = {Social isolation modulates appetite and avoidance behavior via a common oxytocinergic circuit in larval zebrafish}, journal = {Nature communications}, volume = {13}, number = {1}, pages = {1-17}, ISSN = {2041-1723}, year = {2022}, type = {Journal Article} } @article{RN46, author = {Welsh, Christina A and Stephany, Céleste-Élise and Sapp, Richard W and Stevens, Beth}, title = {Ocular dominance plasticity in binocular primary visual cortex does not require C1q}, journal = {Journal of Neuroscience}, volume = {40}, number = {4}, pages = {769-783}, ISSN = {0270-6474}, year = {2020}, type = {Journal Article} } @article{RN24, author = {Westerling-Bui, Amy D and Fast, Eva Maria and Soare, Thomas W and Venkatachalan, Srinivasan and DeRan, Michael and Fanelli, Alyssa B and Kyrychenko, Sergii and Hoang, Hien and Corriea, Grinal M and Zhang, Wei}, title = {Transplanted organoids empower human preclinical assessment of drug candidate for the clinic}, journal = {Science advances}, volume = {8}, number = {27}, pages = {eabj5633}, ISSN = {2375-2548}, year = {2022}, type = {Journal Article} } @article{RN35, author = {Wolff, Steffen BE and Ko, Raymond and Ölveczky, Bence P}, title = {Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution}, journal = {Science advances}, volume = {8}, number = {8}, pages = {eabk0231}, ISSN = {2375-2548}, year = {2022}, type = {Journal Article} } @article{RN84, author = {Ximerakis, Methodios and Holton, Kristina M and Giadone, Richard M and Ozek, Ceren and Saxena, Monika and Santiago, Samara and Adiconis, Xian and Dionne, Danielle and Nguyen, Lan and Shah, Kavya M}, title = {Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types}, journal = {bioRxiv}, year = {2022}, type = {Journal Article} } @article{RN91, author = {Ximerakis, Methodios and Holton, Kristina M and Giadone, Richard M and Ozek, Ceren and Saxena, Monika and Santiago, Samara and Adiconis, Xian and Dionne, Danielle and Nguyen, Lan and Shah, Kavya M}, title = {Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types}, journal = {bioRxiv}, year = {2022}, type = {Journal Article} } @article{RN28, author = {Xu, Han and Lee, Andy and Sun, Lu and Naveh, Gili RS}, title = {3D Imaging of PDL Collagen Fibers during Orthodontic Tooth Movement in Mandibular Murine Model}, journal = {JoVE (Journal of Visualized Experiments)}, number = {170}, pages = {e62149}, ISSN = {1940-087X}, year = {2021}, type = {Journal Article} } @article{RN17, author = {Yu, Houqing and Kamber, Roarke A. and Denic, Vladimir}, title = {The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast}, journal = {eLife}, volume = {11}, ISSN = {2050-084X}, DOI = {10.7554/elife.74531}, url = {https://dx.doi.org/10.7554/elife.74531}, year = {2022}, type = {Journal Article} }