Conserved interfaces mediate multiple protein–protein interactions in a prokaryotic metabolon

Publication information:

, , , V A, , I S. Conserved interfaces mediate multiple protein–protein interactions in a prokaryotic metabolon. Nature Publishing Group UKLondon; 2025.

Abstract

imageimageA map of transient and weak interactions among members of the E. coli 1-carbon metabolon is delineated, and enzymes that use a conserved dedicated interface to engage in such PPI are uncovered. Such complexes speed up enzymatic reactions ...